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The same signaling pathway was attenuated by treating spontaneously hypertensive rats with another H 2 S donor, GYY4137, leading to inhibition of myocardial infarction [236]

But in practice, and especially with regard to synthetic and recombinant peptide forms, there are some considerable potential safety concerns: Immunogenicity Most notably, per a 2020 assessment on therapeutic peptide safety, synthetic and recombinant peptides pose the risk of immunogenicity the ability of a substance to provoke an immune response.15 An immunogenicity-inducing peptide, when introduced to the body, would cause the bodys immune system to perceive the peptide not as a medication but as a threat

Almost all the existing data on BPC-157 comes from a single group of researchers in Croatia