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HSK31858 research results in COPD animal models are equally promising, with this compound demonstrating significant anti-inflammatory activity, effectively reducing inflammatory cell counts and pro-inflammatory cytokine levels in bronchoalveolar lavage fluid ( 5 Development progress of major DPP1 inhibitors Multiple DPP1 inhibitors have advanced to clinical research phases, with the most prominent including brensocatib, BI 1291583, and HSK31858

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doi:10.1111/dom.14239 Kolahdouz Mohammadi R, Hosseinzadeh-Attar MJ, Eshraghian MR, et al