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Some research suggests MPS as a reflex disorder caused by a reverberating circuit of sustained neural activity.[6,7,8] Chronic myofascial pain is usually a result of, and sometimes a product of, both emotional influences and physical factors.[6] According to Fricton et al ., MPS is a regional muscle disorder that is associated with several behavioral, psychosocial, and cognitive contributing factors.[5,9,10,11,12,13,14,15] Once the contributing factors are recognized, they should be minimized

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The scientific rationale for the blend is based on these complementary mechanisms rather than on dedicated studies of the combined formulation