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Both treatments offer distinct benefits, making them suitable for different preferences and health goals

Although elemental selenium, selenium dioxide, and selenium sulfide exhibit limited bioavailability, compounds such as selenite, selenate, and selenium-enriched amino acid analogs are more amenable to absorption, particularly when synergized by vitamins A, D and E ( Figure 1 Selenium is metabolized through the liver, and synthesized and exported to selenoprotein P (SelP), which is eventually secreted into the bloodstream, serving as a vital conduit for the distribution of selenium to peripheral tissues or organs ( The biological effects of Se are exerted primarily through the form of selenoproteins synthesized by the selenometabolic system

1040 of these patients underwent liver biopsy before treatment and were included in the study

van Elderen, S