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Additionally, Key Qualifying variants were Pathogenic/Likely Pathogenic, or Clinical based upon the presence of a corresponding diagnosis

doi: 10.1016/j.celrep.2017.12.077 59 DaiEChenXLinkermannAJiangXKangRKaganVEet al

Methods for introduction of nonviral vectors into an animal Nonviral vectors encoding products useful in gene therapy can be introduced into an animal by means such as lipofection, biolistics, virosomes, liposomes, immunoliposomes, polycatiomnucleic acid conjugates, naked DNA injection, artificial virions, agent-enhanced uptake of DNA, ex vivo transduction