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Description

We found that simultaneous Cdkn1c hypomethylation and C/EBP overexpression in pancreatic -cells causes a synergistic decrease in pancreatic -cell mass

CRISPR Therapeutics is pushing beyond rare diseases and into cardiometabolic territory with its in vivo editing platformdebuting first-in-human data for CTX310 (targeting ANGPTL3) and preclinical results for CTX340 (targeting AGT) at AHA 2025