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demonstrated that simvastatin alone significantly reduced bacterial load in Mtb-infected PBMCs via enhanced production of natural killer T cells, upregulation of co-stimulatory molecules in monocytes, increased the secretion of IL-1 and IL-12p70, and promotion of apoptosis and autophagy in monocytes (139)

(48) reported that administering 80 mg/kg BW/day of ASTX to HFD-fed mice for 14 weeks was effective in significantly reducing liver weight relative to body weight

Example 1 Step 1: weighing injection water with the prescription amount of about 30 percent, cooling to 20-30 , and filling high-purity nitrogen into the injection water to replace oxygen in the solution until the oxygen content in the solution is less than 1.5 ppm