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DTX, leelamine, ferrocifens, ARV-825, vemurafenib, Bcl-2 siRNA, BRAF siRNA, and the BRAF V600E peptide were used in combination with lipid-based nanosystems in systemic applications (Table 3)

A concept suggested by Casaccia and Bodekke is that OL death in MS lesions could reflect a continuum of injury mechanisms dependent upon the specific insults and its severity 36