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Therefore, the need for new therapies able to cure and prevent the progression of this condition is increasingly urgent

The role of macrophages in aortic dissection

What is worth to summarize here is the fact that several pro-apoptotic stimuli induce an early extrusion of GSH from cells leading to a widespread mitochondrial damage and to cytochrome c release into the cytosol, the starting condition for apoptotic intrinsic pathway commitment