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Platelet cell surface disulfide isomerase mediated S-Nitrosoglutathione consumption

Consequently, this design aggravates the redox imbalance, causing a rapid increase in ROS in the short term in vitro, ultimately leading to the downstream signaling pathway activation and apoptosis of AML cells

Thus, elucidating the molecular basis of SCI is crucial for improving patient outcomes

doi: 10.3389/fphar.2022.906301 Received 28 March 2022 Accepted 26 April 2022 Published 01 June 2022 Volume 13 - 2022 Edited by Shuai Ji, Xuzhou Medical University, China Reviewed by Tanaya Roychowdhury, Indian Institute of Chemical Biology (CSIR), India Rudradip Pattanayak, University of Alabama at Birmingham, United States Lina Wen, Capital Medical University, China Updates Copyright 2022 Chen, Qi, Ma, Xiao, Liu, Xia, Xiang, Zeng and Tang