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Ent1 and Ent2 behave as different binders, and from our results, it can be speculated that Ent1 forms a more stable complex and likely plays a pivotal role in connecting the actin cytoskeleton to the membrane

Our approach at Cymbiotika is rooted in these pillars

We first assessed the expression of REST in different organs and found moderate expression in the heart, liver, spleen, lung, and kidney, as well as lower levels in the brain (Supplemental Figure 1, A and B