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If you develop severe allergic reactions such as difficulty breathing, facial swelling, or widespread rash after a B12 injection, call 999 or go to A&E immediately, as these may indicate anaphylaxis, though this is extremely rare

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Similarly, BioNTechs mRNA-based BNT153 and BNT152, encoding IL-2 and IL-7, respectively, are in a Phase I trial (NCT04710043) for advanced solid tumors (200)