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Xu, J., Chen, H., Qian, H., Wang, F

Vitamin B12 is an essential cofactor in the folic acid metabolic cycle, both involved in the remethylation of Hcy to methionine (69)

(2018) 50:e13050

On cancer cell lines and tissues, SFN can induce epigenetic modifications, including DNA methylation, an increase in expression of genes like p21 and p16 , and inhibition of HDAC expression