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Senolytic compounds can act by inhibiting these proteins, promoting cell death in senescent cells

Of note, the possible contribution of the particular counteracting effect on the intravenous dextran- or egg whiteinduced anaphylactoid reaction (Duplancic et al., 2014) should also be considered, although not specifically mentioned in this review

A mild concussion with intact blood-brain barrier presents a very different repair challenge than a severe TBI with diffuse axonal injury and widespread inflammation