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Key resistance mechanisms including pathway switching, tumor heterogeneity, and TME support are highlighted

In response to excessive light, plants activate a series of signaling pathways starting from the chloroplast and affecting the entire plant, leading to stress-specific physiological changes

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v - miR-MR147-3p and v-miR-MR66-3p target TMPRSS2 and TNF-, respectively, to effect an adverse clinical symptom via elevating the expression levels of TMPRSS2 and TNF- [81]