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Phase Ib study design evaluating the safety, pharmacokinetics and pharmacodynamics of selnoflast, a novel NLRP3 inflammasome inhibitor in early-stage PD (P211.007)

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in theory, as oxidative stress increases, NMDA receptor dysfunction is likely to increase (Fig

Further structural characterization of the active compounds would provide deeper mechanistic insight into redox modulation and antioxidant enzyme regulation