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Advise males with female partners of reproductive potential to use effective contraception during treatment with pemetrexed and for 3 months after the last dose [see Use in Specific Populations (8.1, 8.3) and Clinical Pharmacology (12.1)]

10.1016/0143-4179(88)90061-3 138 VenihakiM.SakiharaS.SubramanianS.DikkesP.WeningerS

2016;8:e2016055

Oe S, Miyagawa K, Honma Y, Harada M (2016) Copper induces hepatocyte injury due to the endoplasmic reticulum stress in cultured cells and patients with Wilson disease