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338 Ferroptosis in autoimmune diseases Autoimmune diseases, such as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and myasthenia gravis (MG), are caused by disorders in autoimmune tolerance and the bodys immune response to the self-antigen

Changes in mitochondrial structure and morphology have also been observed, such as increased mitochondrial membrane density, decreased or disappeared mitochondrial cristae, and ruptured outer mitochondrial membranes (153)