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Representative samples of the most atypical parts of the nevus should be biopsied, often guided by dermatoscopy

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Future research should systematically elucidate the dynamic regulatory network of amino acid metabolism during the progression of thyroid cancer, focusing on analyzing the functions of epigenetic key nodes such as glutathione S-transferase (GST) and microRNA-137 in the drug resistance and carcinogenesis process, and exploring the therapeutic potential of these nodes