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Another difference to be considered between our two cell models is the number of donors

Neuropharmacology 131 , 364376 (2018)

Characterization of the endotheliopathy, innate-immune activation and hemostatic imbalance underlying CAR-T cell toxicities: laboratory tools for an early and differential diagnosis

The accumulation of ROS has been demonstrated to trigger the phosphorylation and activation of the key kinase p38 MAPK, suggesting that ROS is a potential activator of the MAPK signaling pathway [75]