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BCAA supplementation can reproduce the hyperfunction of CD8 + T cells and show a synergistic effect with anti PD-1 immunotherapy in NSCLC patients

As seen above, there are 4 principal interactions by which the gut influences the brain

DICP 1990;24:860

Sorafenib, a multiple kinase inhibitor and FDA approved drug, was revealed to induce ferroptosis and exhibit anti-tumor effects in various cancer cell lines such as hepatocellular carcinoma cells, human kidney cancer cells and nonsmall cell lung cancer [131, 132]