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(Where the start of sleep is delayed, and sufferers then struggle to wake up in the morning)

doi: 10.1016/j.ajpath.2016.06.003

Transcriptional modulators of the PGC-1/ERR/PPAR regulatory axis The expression of PGC-1, a master regulator of mitochondrial biogenesis and cellular metabolism, is precisely controlled by a network of upstream transcription factors