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Furthermore, by scavenging the O2-accumulation caused by H2O2, esculetin (100 M) protects human leukemia NB4 cells from oxidative stress damage (24,25)

PLoS ONE 9(6): e98387

Modified GRF (1-29) is a synthetic modification of growth hormone releasing factor with D-Ala, Gln, Ala, and Leu substitutions at positions 2, 8, 15, and 27 respectively substitutions that create a significantly more stable and longer-acting compound than either native GRF (1-29) or Sermorelin, while maintaining the same receptor interaction profile at the GHRH receptor