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Sa12b-Modified functional self-assembling peptide hydrogel enhances the biological activity of nucleus pulposus mesenchymal stem cells by inhibiting acid-sensing ion channels

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Some hemiaminals can be observed in aqueous solution, such as the HCHO adduct with Tris buffer and one product derived from the inhibitor/competitive substrate Meldonium after its reaction with -butyrobetaine hydroxylase (this hemiaminal is in equilibrium with an oxazolidine) 54

However, its loss may also serve as an adaptive rather than causal mechanism