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Data on DES is sourced from the State Medicare Modernization Act (MMA) file of dual eligible beneficiaries, which each of the 50 States and the District of Columbia submit to CMS at least monthly

The gut microbial population harbors a vast gene pool that influences the diversity of messenger RNA (mRNA), DNA methylation, and non-coding RNAs (such as miRNAs, lncRNAs, and circRNAs) within the host (177, 178)