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IRE1A Stimulates hepatocyte-derived extracellular vesicles that promote inflammation in mice with steatohepatitis

doi: 10.1016/j.cell.2022.05.017 53 MartensYAZhaoNLiuCCKanekiyoTYangAJGoateAMet al

Crosses the blood-brain barrier

Given the substantial behavioral variability characteristic of ASD, insufficient sample sizes represent an important source of bias in preclinical studies