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doi: 10.3390/ijms22126493 30 JenkinsNLJamesSASalimASumardyFSpeedTPConradMet al

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FDA's evaluation concluded that the criteria weighed against placement on the list, citing inadequate physicochemical characterization, immunogenicity concerns from impurities and aggregates, lack of clinical effectiveness data for any approved use, and absence of published human exposure data for the proposed subcutaneous and topical routes

It plays a central role in neutralizing free radicals, supporting liver detoxification, and maintaining immune function