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LC is required for long-chain fatty acid transport metabolism in mitochondria and consequently for energy metabolism

Introducing another metabolic modulator during this window confounds attribution because you cannot separate KLOW's residual effects from the new compound's direct effects

Direct oral anticoagulants (DOACs) are preferred for stroke prevention in AF due to their convenience, fixed dosing, and lower bleeding risk compared to vitamin K antagonists [10]

Furthermore, this finding provides a possible explanation for the reported mild hepatotoxicity associated with the clinical use of bile acid sequestrants in human patients