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The increase in the number of periurethral epithelial and stromal cells characterizes BPH histopathologically due to the maladjustment of cell proliferation and death [3]

Diquat exacerbates oxidative stress and neuroinflammation by blocking the autophagic flux of microglia in the hippocampus

Effects seen at those exposures cannot be assumed to occur at physiologic levels, and pushing systemic exposure high enough to reproduce them in a whole organism is precisely what raises the copper-loading concern

As G-GTP and G each has the capacity to convey cellular signals we will discuss them separately, focusing primarily on G-GTP