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Nevertheless, in these registries, the association between elevated B12 and solid cancers was not adjusted for all elevated B12-related causes, except for excessive vitamin B12 supplementation in the Danish registry and alcohol misuse in the British registry

Lower density can lead to weaker bones and even osteoporosis, a condition that most people are unaware they can have until the bone breaks

This finding suggests possible non-monotonic dose-response (NMDR) effects, where low-dose exposure may produce different biological responses compared to higher exposure levels (79)

A full HLA match with a sibling or unrelated donor is recommended preferably before the age of 12