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Science 122:501514 Eagle H (1959) Amino acid metabolism in mammalian cell cultures

The first meta-analysis was published in 2012 and featured 15 studies (n=360 subjects) with an overall outcome of beta-alanine improving the exercise outcome measures compared to control (p=0.002 with an overall effect size (ES) of 0.374) and the majority of the performance effects being demonstrated over 1 to 4 min of high-intensity exercise (Hobson, Saunders, Ball, Harris, & Sale, 2012)