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However, despite early recruitment of highly mutated B-cell clones reflecting cross-reactive hCoV memory, these responses are mostly nonneutralizing [92, 94,95,96,97] and decline between three and six months after infection, whereas de novo-generated B-cell responses expand and largely contribute to the nAb response [94]

Huang T, Gu J, Zhang K, Sun L, Xue X, Zhang C, et al

Environmental Science & Technology, 851(2): 158247 Prasedya E, Kurniawan N, Kirana I, Ardiana N, Abidin A, Ilhami B, Jupri A, Widyastuti S, Sunarpi H, Nikmatullah A (2022)