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Journal of Gerontology Series A: Biological Sciences and Medical Sciences, 78 (12), 24352448

doi: 10.1093/intimm/dxw002 [DOI] [PMC free article] [PubMed] [Google Scholar] 492

A peer-reviewed overview of short peptides for hair loss in the PMC NIH database confirming that copper peptide GHK-Cu stimulates VEGF production in dermal fibroblasts, supports microvascular angiogenesis, and facilitates collagen and GAG synthesis at the follicle level

Anticancer activity The effects of methanolic extract of aerial part of plant on human cancer cell lines (including MCF7, an estrogen-dependent breast adenocarcinoma cell line, A549, a non-small cell lung cancer cell line, and HeLa, a cervical cancer cell line) and normal cell lines (including A7R5, a vascular smooth muscle cell line, and 293 T, a human embryonic kidney cell line transformed with SV40largeTantigen) were assessed Inhibitory concentrations for MCF7 (IC50 = 190 ng/mL), HeLa (IC50 = 284 ng/mL), A7R5 (IC50 = 382 ng/mL) and 293 T (IC50 = 317 ng/mL) cells were all much higher than those for A549 (IC50 = 778 ng/mL) which had a much less pronounced impact [63]