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Description

The direct antioxidant and free radical scavenging properties of melatonin are mainly due to its electron-rich aromatic indole ring, which makes it a potent electron donor that can significantly reduce oxidative stress 3,22

The latter was suspended in 300 mL of distilled water and fractionated with CHCl 3 to give 60 g of CHCl 3 fraction, which was chromatographed on silica gel column (800 g, 100 5 cm) using n- hexane/EtOAc gradient