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In recent years, we added an epigenetic component to the Allostasis/Allostatic load model to describe how non-shared environmental experiences may set each individual on a somewhat different trajectory of development that determines either adaptive or maladaptive responses (behavior, systemic function and vulnerability to disease) to subsequent novel experiences as the life course unfolds [20]

The patients data were extracted from the attending physicians progress notes, results from lab measurements, and patient seizure diaries that ranged from June 2016 to June 2021

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Suzuki H, Kaizuka T, Mizushima N, Noda NN