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each R46, R47, R48 and R49 are independently hydrogen, alkyl, substituted alkyl, aryl, substituted alkyl, arylalkyl, substituted alkyl, eye lo alkyl, substituted alkyl, cycloheteroalkyl, substituted cycloheteroalkyl, heteroalkyl, substituted heteroalkyl, heteroaryl, substituted heteroaryl, hetero arylalkyl, substituted hetero arylalkyl, -NR50R51, -C(O)R50 or -S(O)2R50 or optionally R50 and R51 together with the atom to which they are both attached form a cycloheteroalkyl or substituted cycloheteroalkyl ring

10.1016/j.foodchem.2025.143956 Food Chem

Plummer Ryan J

In PD, progressive degeneration of dopaminergic neurons disrupts this delicate balance, reducing striatal dopamine levels and impairing the direct and indirect pathways