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2018 (Curr Neuropharmacol, PMID 29879879)

Oral contraceptives: May lower serum vitamin B12 concentrations (34)

To determine which proteoforms may be associated with pathological and cognitive diagnosis on a continuous scale, avoiding subjective between-class limits, parallel linear models were fit with quantification ratio of each peptide as outcome variables, and global cognition Z-score, global pathology Z-score, age at death, sex, post-mortem interval (hours) and number of years in education as explanatory variables

Results: The effects start to appear within 3-7 days, with full results visible in about 2 weeks