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Clinicians utilizing these findings have developed targeted treatment protocols, often referred to as the "Brewer Protocol," which focus on eradicating fungal colonization in the sinus cavities using biofilm disruptors and intranasal antifungals

Trayhurn P, Beattie JH

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involving 20 patients with PD found that twice-daily inhalation of 1.21.4% hydrogen over 4 weeks did not lead to improvements in UPDRS scores, olfactory function, or the ability to perform activities of daily living