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Marker groups consisting of SDC2 and SEPT9 were detected in urine sediment of CRC cases with a specificity of 70%, showing promise for non-invasive CRC detection through urine liquid biopsy ( SEPT9 plays a crucial role in cell division, and its hypermethylation process is linked to carcinogenesis and can alter the conformation of gene sequences

+ Common signs of low B12 include persistent tiredness or low energy, brain fog or poor concentration, pins and needles or numbness in the hands and feet, a sore or red tongue, mouth ulcers, low mood, and looking pale

People with hypothyroidism or patients undergoing thyroid treatment should first consult a health professional

& Barone, V