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Mechanistically, early-life microbial colonization patterns exert long-term immunological consequences, exemplified by Clostridium difficile establishment at 1 month predicting asthma development by age 67 years (van Nimwegen et al., 2011)

The twenty-six week completion rate in Study 2 was 74%

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[351] While these gene therapy products may have a similar goal to clotting factor products, in that both products are designed to improve outcomes for patients with hemophilia, gene therapy products prompt the body to make clotting factors, but are not clotting factors themselves