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doi: 10.3390/biom10030393 60 FantiniJ.YahiN.GarmyN

Oxidative stress is caused by an overproduction of oxidants or unbalanced defence mechanisms played by antioxidants and their related enzymes

In addition to these questions, you must also consider patient comfort to ensure compliance

Several studies using reconstituted ISC machineries of mouse, human, yeast, and bacteria have reported a key function of frataxin in this process, but most of these reconstructions used incomplete ISC machineries, lacking FDX2 and FDXR (Figure 2B, red chart), which has led to a misinterpretation of the functional role of frataxin