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The body does not exclusively target fat stores during periods of severe energy restriction

On the other hand, Kupffer cells, upon activation by endotoxins (including lipopolysaccharide, LPS) or superoxide anions (O 2 ), will then produce more ROS through stimulation of NADPH-dependent oxidases (NOXs), and the redox-sensitive transcription factor nuclear factor-B (NF-B)-mediated pro-inflammatory storm of cytokines, chemokines, and cell adhesion molecules (CAMs) [36]

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This result suggests that BPC 157-treated rats exhibit continual improvement in motor function even before tissue recovery, as observed by microscopy assessment