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A Phase 1 registry record has no posted efficacy result, and a small uncontrolled knee-pain report does not establish benefit

10.1016/j.freeradbiomed.2018.05.075 Free Radical

Most features of CKD-MBD are usually present by the time eGFR falls below 45 (stage 3b), though bone disease can begin as soon as stage 2 (eGFR 60 to 89)

(7) M.Hrelec et al (2009) Abdominal aorta anastomosis in rats and stable gastric pentadecapeptide BPC 157, prophylaxis and therapy Journal of Physiology and Pharmacology, 2009 Dec:60 Suppl 7:161-5