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39 LancasterE

The SHREAD gene therapy platform for paracrine delivery improves tumor localization and intratumoral effects of a clinical antibody

M., Khramtsova G., Olopade O., Lee B

At the microbial level, taxa such as Lactobacillus and Bifidobacterium favour TRP availability for 5-HT synthesis, whereas enrichment of pro-inflammatory Proteobacteria enhances immune-driven IDO activation and KYN production [175], directly linking microbial ecology to mood-relevant neurochemical pathways