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Senescent neutrophils in circulation, however, were found to return to the bone marrow for final clearance upon upregulating expression of the cytokine receptor CXCR4, a central regulator of neutrophil trafficking under homeostatic conditions [52]

L.WrightA

Collins, and C

Although 12 h incubation with biotin was enough to label some interactors, we chose to perform all experiments using 24 h incubation to maximise the detection of weak and low abundance proximity proteins, and the potential to identify cargo proteins transiting through the sub-domains (Supplementary Fig