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Figure 1: Kaplan-Meier Curve for Overall Survival in KEYNOTE-189* *Based on the protocol-specified final OS analysis Initial Treatment in Combination with Cisplatin The efficacy of pemetrexed was evaluated in Study JMDB (NCT00087711), a multi-center, randomized (1:1), open-label study conducted in 1725 chemotherapy-naive patients with Stage IIIb/IV NSCLC

Many patients end up using both, which is perfectly reasonable because the mechanisms barely overlap

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