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In contrast, during chronic or infected wound states, the pH shifts to alkaline levels (pH 79) as a result of microbial activity 53,54

Wilcken DEL and Wilcken B (1976)

Since 2015, the humanized anti-CD22 monoclonal antibody epratuzumab has been investigated for the treatment of SLE, holding promise for patients with moderate to severe active disease (142144)