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Pernicious anaemia is caused by a deficiency in vitamin B12, due to atrophic gastritis, an autoimmune condition (immune system destroys self), in this case the parietal cells of the stomach that produce intrinsic factor, a glycoprotein that binds to vitamin B12 in the stomach and is essential for normal absorption of vitamin B12 in the small intestine into the blood

But newer iron formulations are much safer, and serious risks are rare

This muscle-sparing effect during weight loss is particularly valuable for maintaining metabolic rate, physical function, and long-term weight loss sustainability, as preservation of lean mass helps prevent the metabolic adaptations that typically promote weight regain

Air quality status and health impact