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reported the feature importance of both cations and ligands through the analysis of their machine-learning models, such as random forest feature importance and permutation importance, none of the cation features were even in the top 10, despite n being determined by the interaction between cation and ligand 8

Therefore, while targeting magnesium homeostasis is a plausible adjunctive strategy specifically within the context of APAP toxicity, its general applicability across the etiologically diverse landscape of DILI remains highly speculative

Maintaining intestinal barrier integrity is therefore essential to prevent LPS translocation and limit disease progression (53)

This increase in phosphate levels is thought to stimulate FGF23, resulting in phosphaturia and the inhibition of 1.25-dihydroxyvitamin D to maintain the phosphate balance