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Phosphoproteomics reveals rewiring of the insulin signaling network and multi-nodal defects in insulin resistance

Similar content being viewed by others Introduction The cohesin complex tethers sister chromatids from their synthesis during DNA replication until their separation at anaphase, a process termed sister chromatid cohesion (Nasmyth et al, 2000

Previous investigations have highlighted elevated NNMT expression in the liver and white adipose tissue (WAT) of diabetic mice and obese, with evidence suggesting that downregulating NNMT expression can mitigate diet-induced IR and obesity (Kraus et al., 2014